A Study of Leukocyte Migration Inhibition Factor in Behcet's Syndrome / 대한피부과학회지

This study was undertaken to investigate the immunological mechanism of Behqet s syndrome, considered to be important in the pathogenesis of the disease. Seventy- three patients with complete, incomplete and suspected types of Behget's syndrotne were tested for leukocyte migration ingibition factor(LIF), one of the lymphokines. The results were as follows : 1. There was no difference between the average LIF activity of all the patients and that of eontrol. 2. LIF activity of complete type, according to Shirnizus classification, was significaritly lower than the control value. 3. LIF activity of ocular type, according to Lehners classification, was signficantly lower than the control value. 4. LIF activity for patients with 4 clinical symptoms was well below the value for patients with less symptomes 5. For patients with single clinical symptom, LIF activity of complete type was well below the values of incomplete and suspected types. 6. In suspected and mucocutaneous types, LIF activity was low when the patients showed two clinical symptoms than one. Thus, LIF activity was low for patients with complete, ocular and neurological types and with multiple symptorns.

A Case of Keratosis Palmoplantaris Nummularis / 대한피부과학회지

A case of 39-year-old male with keratosis palmoplantaria nummularis was reported. The skin lesions were characterized by the presence of painful focal keratoses on the plantar pressure points. Biopsy of a keratotic plantar lesion revealed excessive hyperkerstosis, hypergranulosis, focal hypogranulosis, and acanthosis in the epidermis. We could observe aymptomatic relief of this patient who was treated with mixture of corticosteroid, 25% urea and 2.5% salicylic acid.

Behcet's Syndrome in Korea: A Look at the Clinical Picture

Behcet's syndrome is being detected increasingly in Korea. To collect and document information concern- ing the clinical picture as it is records of patients seen in our clinic in the period between November 1983 and March 1986 were used as source material. In summary, it was found that (1) the total number of patients who had two majors symptoms at least were 410, including 170 men and 240 women; (2) Patients in their thirties were the most common, the mean age being 34.6 years; (3) according to Lehner's classification, the order of frequency of the different types was mucocutaneous (52%), ocular (33), arthritic (14%) and neurologic (1%) and according to Shimizu's classification, it was incomplete (39%), suspected (37%), and complete (24%); (4) oral ulcers, which had observed in 407 patients were the most frequent major symptom, followed by genital ulcers in 338 patients.